In response to the mechanism of chemical burns, an efficient decontamination requires: to remove the chemical from the surface to prevent further penetration; to stop polyvalently the six kinds of aggressive chemical reactions; to be able to stop the penetration of the aggressive product into the tissues. Plastic Reconstr Surg 2003 ; 111 : 1918-1921. The intervention period for rinsing with water is very short in order to obtain an optimum result. Access to water is indeed generally easy. Saldanha IJ, Lindsley KB, Lum F, Dickersin K, Li T. JAMA Ophthalmol. Diphoterine® Eye Products willows 2020-10-23T14:08:31+00:00. Methods: Shelf Life . Rinsing with water does not allow any reduction in the hazard represented by the chemical product. Safety of dermal diphoterine application: an active decontamination solution for chemical splash injuries. Cutan Ocul Toxicol. When a splash occurs, the chemical product is deposited on the surface of the tissue. Outcomes are significantly improved when compared to water or a physiologic solution equivalent. It is definitely an emergency rinsing solution for eye or skin splashes of chemical products. HHS The chemically reactive sites of this molecule will be capable of reacting with the corrosive or irritant chemical products, thus preventing their reaction with the biological components of the tissues. Certain studies have shown that side effects due to phosphates can occur in some cases. Four characteristics provide its activity against splashes of chemical products. Hence, emergency management requires one to: What are the advantages and limitations of rinsing with water? This mechanical action is the main effect of the rinsing. Cointervention – chloramphenicol eye drops nightly for 22 days until euthenised: Slit lamp exam and intraocular pressure (days 1, 3, 7, 12, 18, 22) Ascorbic acid (days 1, 7, 22) – marker for systemic oxidative stress Histological examination (day 22) Diphoterine more effective than immediate irrigation with saline in reducing … FAQ – Frequently Asked Questions about Diphoterine® solution, Rinsing instructions of chemical burns with DIPHOTERINE® and HEXAFLUORINE® solutions, Eliminate the chemical product present on the surface of the skin or the eye, Halt penetration of the chemical product inside the tissue and remove the chemical product that has already penetrated. [4], [1] Cavallini, Annals of Burns and Fire disasters 2004, vol XVII-2, 84-87 et Cavallini, European Journal of Anaesthesiology 2004, 21, 389-392 SKU: LPMD6 Categories: Chemical Splash Products, Diphoterine® Eye Products. Its physical and chemical characteristics allow decontamination in case of splashing of chemical products on the skin or in the eye. These products are liable to cause serious lesions that may be limited by first-aid use of Diphoterine® solution. Is it time for a change in the approach to chemical burns? Any study type published through a peer-reviewed journal up to May 2016 was considered eligible. Water does not make it possible to eliminate the chemical product that has already passed into the skin or the eye. While used extensively in Europe and Canada, it is has not been approved by the United States Occupational Safety and Health Administration (OSHA) as an alternative to the water-rinse method due to a lack of evidence of its safety and efficacy on human subjects. Get contact details and address | ID: 19167534991 Consequently, if the chemical product has disrupted physiological balance, rinsing with water will not help to restore a physiological state.